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The first place that a translated protein is modified is in the lumen of the rough endoplasmic reticulum. This is generallyglycosylation, or the addition of sugar molecules to the protein. This happens when the translated protein enters the lumen of the ER through its pore. The signal sequence (very first part of a translated protein) enters the pore aided by the signal sequence recognition protein SRP. In the rER lumen the protein assumes its tertiary shape as well. Glycosylation also occurs in the Golgi apparatus, specifically, the first modification in the Golgi is in the first part of the Golgi, the CIS Golgi network. The Golgi packages and modifies the protein for their distribution.
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∙ 12y ago
Wiki User
∙ 11y agono
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What is the difference between a dominant gen and a recessive gen?
In one allele (recessive) the transcriptional or post translational processes does not occur due to some modification and doesn't express while in other allele it occur (dominant).
How is excision to make the completed mRNA accomplished?
post transcriptional modifications such as cutting and splicing of exons!
After mRNA has been transcribed in eukaryotes?
The mRNA would then undergo post-transcriptional modifications before being translated by ribosomes.
What are some specific studies of gene silencing?
Gene silencing has several specific studies including Meiotic, Transcriptional, Post-transcriptional, and Cellular components of gene silencing. Gene silencing is basically when scientists turn off a gene, so to speak.
Do all proteins start with methionine?
Proteins have undergone post-transcriptional modifications, thus may not start with methionine after it has been modified.
What is the process of post-transcriptional modification?
Post-transcriptional modification is a process in cell biology by which, in eukararyotic cells, primary transcript RNA is converted into mature RNA. A notable example is the conversion of precursor messenger RNA into mature messenger RNA (mRNA), which includes splicing and occurs prior to protein synthesis. This process is vital for the correct translation of the genomes of eukaryotes as the human primary RNA transcript that is produced as a result of transcription contains both exons, which are coding sections of the primary RNA transcript.
What is the difference between a dominant gen and a recessive gen?
In one allele (recessive) the transcriptional or post translational processes does not occur due to some modification and doesn't express while in other allele it occur (dominant).
Post translational modification occurs in which cell organelle?
Post translational modification occurs in ribosomes.
How is mRNA stabilized before leaving the nucleus for translation?
Before leaving the nucleus, the mRNA is modified (post-transcriptional modification). It is protected from ribonucleases by adding a 5' cap and a (3') poly A tail. These modifications help to stabilise the mRNA by preventing degradation by nucleases.
Eukaryotes show which kinds of control mechanisms is it transcriptional transcript processing translational post translational or all of these?
all
How is excision to make the completed mRNA accomplished?
post transcriptional modifications such as cutting and splicing of exons!
After mRNA has been transcribed in eukaryotes?
The mRNA would then undergo post-transcriptional modifications before being translated by ribosomes.
What are some specific studies of gene silencing?
Gene silencing has several specific studies including Meiotic, Transcriptional, Post-transcriptional, and Cellular components of gene silencing. Gene silencing is basically when scientists turn off a gene, so to speak.
Do all proteins start with methionine?
Proteins have undergone post-transcriptional modifications, thus may not start with methionine after it has been modified.
What is the function of snRNP?
The action of snRNPs is essential to the removal of introns from pre-mRNA, a critical aspect of post-transcriptional modification of RNA, occurring only in the nucleus of eukaryotic cells. Additionally, U7 snRNP is not involved in splicing at all, as U7 snRNP is responsible to process the 3′ stem-loop of histone pre-mRNA.
What are four ways transcription is repressed?
Transcriptional repressors: Proteins that bind to specific DNA sequences near the promoter region of a gene and block the binding of transcription factors and RNA polymerase, preventing transcription initiation. Chromatin remodeling: Repressive chromatin modifications, such as DNA methylation or histone deacetylation, can make the DNA inaccessible to transcription machinery, hindering transcription initiation. Transcriptional interference: Overlapping or nearby transcriptional events can interfere with each other, leading to the repression of one or both transcription processes. RNA-mediated repression: Certain non-coding RNA molecules can bind to mRNA transcripts, inhibiting their translation and subsequently repressing gene expression at the post-transcriptional level.
Gene expression might be altered at the level of post-transcriptional processing in eukaryotes rather than prokaryotes because of what?
Eukaryotic exons may be spliced in alternative patterns
