Vitamins and Supplements

Where is b12 absorbed in the body?


Top Answer
User Avatar
Wiki User
2009-02-15 21:32:04
2009-02-15 21:32:04

Vitamin B12 is absorbed in the terminal ileum (the last part of the small intestine). The process of absorption occurs by dietary B12 becoming bound to R-protein in the saliva, the B12 is then cleaved from R-protein by the acidic conditions in the stomach. Gastric parietal cells secrete a substance called Intrinsic Factor, which binds the B12. In the terminal ileum there are receptors for intrinsic factor and both are absorbed. Problems with this absorption can occur if the body makes auto-antibodies to intrinsic factor, this means there is problems with B12 absorption and a condition called pernicious anaemia can result. The answer you wanted is the first line, but I hope the extra information is either helpful or of interest. Pete (medical student in the UK)

User Avatar

Related Questions

It takes approximately 24 hours for the absorption of vitamin B12. For quicker absorption, you can get a B12 shot.

The only nutrient that can't be absorbed is ......... Vitamin B12.

If you have this problem, you might have a problem in your small intesine's terminal ileum where B12 is absorbed.

Vitamin B12 is commonly found in fortified food s and animal products. This is usually absorbed into the blood by the ileum which is part of the small intestines.

Salt is absorbed into the body via the liver.

Neither plants nor animals are independently capable of constructing vitamin B12 (Only bacteria have the enzymes required for its synthesis). B12 is replenished in the body from dietary sources.

What would cause high levels of vitamin b12

Pernicious anemia is due to a deficiency of a vitamin called intrinsic factor, which is normally produced by cells of the stomach. Intrinsic factor is required for the absorption of vitamin B12, so if intrinsic factor levels are insufficient, vitamin B12 will not be absorbed well. So administration of vitamin B12 will only help treat vitamin B12-deficiency anemia if vitamin B12 can be absorbed, and this can only happen if there are adequate levels of intrinsic factor to begin with. Patients with pernicious anemia do not have adequate intrinsic factor levels, so they will not be helped by vitamin B12 treatment since they can't absorb it well enough.

Neither plants nor animals synthesize vitamin B12: only bacteria make the biologically active form. Animal tissues can store the B12 made by the bacteria, which can then be passed along to carnivores when they eat animal tissue. Ruminants (cows, goats, sheep, giraffes, llamas, buffalo, and deer) have bacteria in their rumens (stomachs) that synthesize vitamin B12, which is then passed down and absorbed by their small intestines. Large carnivores get their B12 from eating these grazers. Your digestive tract also contains B12-synthesizing bacteria, which is one reason that vitamin B12 deficiency disease is rare in humans, even among vegans. Most of the bacteria is in your colon, and B12 is absorbed "upstream" in the ileum, so you don't absorb the B12 that's made in your colon unless it somehow gets back into your upper digestive tract. Feces contain large amounts of active B12. Our ancestors lived in close contact with each other and their farm animals, and they got their B12 by eating unsanitized food. We now live in over-sanitized conditions, and the need for B12 supplementation for vegans is the result of our obsession with cleanliness. If you were raised on an omnivorous diet, you probably have about 2 to 5 milligrams of B12 stored, mostly in your liver. That's at least a three-year reserve. Your body can conserve this supply by reabsorbing B12 from your bile, making your reserves last an average of 20 to 30 years after becoming a strict vegan if you consume no B12. In reality, you do get small amounts of B12 from your intestinal bacteria, unwashed vegetables, and the environment. When you consume vitamin B12, hydrochloric acid in your stomach separates it from any protein to which it may be attached. Then, vitamin B12 combines with a protein made by your stomach called intrinsic factor and is absorbed by your body. Some people have pernicious anemia, a condition where they cannot make intrinsic factor. As a result, they have trouble absorbing vitamin B12 from food and supplements.

You can become anemic if you have a B12 deficiency. The vitamin is needed to make hemoglobin for your red blood cells.

Pernicious Anemia is when the body is unable to absorb the Vitiman B12, meaning your body cannot manifest enough red blood cells for the amount of Oxygen your body needs.

Liver disease (such as cirrhosis or hepatitis) is a medical condition that can increase vitamin B12 in the body. Some myeloproliferative disorders (for example, polycythemia vera and chronic myelocytic leukemia or CML) can also increase vitamin B12 in the body. Vitamin B12 excess is virtually harmful since it is a water-soluble vitamin. It will just be secreted from the body as urine. The conditions themselves are what is cause for concern. The increased vitamin B12 can just be used as an indicator for the disease.

it is absorbed in the small intestine.

B12 is absorbed in the ileum Where the large and small bowel join. Lack of a stomach should not affect the absorption of Oral dosing B vitamins.

That would be in the liver, Bob.

Which type of alcoholic beverage is absorbed the fastest by the body

The majority of them are absorbed in the colon.

i dont know but i know that Vitamin B12 is important for producing cells in the body, such as red blood cells

The Ileum mainly absorbs vitamin B12 and bile salts and whatever products of digestion were not absorbed by the jejunum.

The function of ileum is absorb vitamin B12 and bile salts. If products were not absorbed by the jejunum the ileum would absorb them.

Glucose is the form of sugar most quickly absorbed by the body.

Your body needs B12 to have brain and nervous system functions. B12 is commonly used for the metabolism of a cell, DNA synthesis / regulation, and energy production (from fatty acids). Some people can also have a disorder (perniscious anemia) where their bodies cannot process B12, or their bodies use it up too fast. If a person also has a certain type of tapeworm, the parasite would use up the B12 in their body.

In terms of how your body deals with it, alcohol is basically sugar. It's not absorbed into body fat really, but it is easily converted into body fat.

Copyright ยฉ 2020 Multiply Media, LLC. All Rights Reserved. The material on this site can not be reproduced, distributed, transmitted, cached or otherwise used, except with prior written permission of Multiply.