Los Angeles with 3.8 million people in 2008.
Los Angeles, California
The second largest city in the US is Los Angeles.
Philadelphia
The second one is Chicago.
Los Angeles
LA
The second most populous city not including the surrounding metropolitan area is Chicago.If the surrounding area is included, the second most populous city in the US is Los Angeles, California.
Juneau is the second largest US city by area.
You already answered your question. The second largest city in the USA is Los Angeles.
Los Angeles, CA.
New York City is the largest city in US, and the second largest city in North America. Mexico City is the largest. Toronto Is the largest city in Canada, and the fifth largest city in North America, after Los Angeles and Chicago.
Spokane is the second largest, after Seattle. The metropolitan area of Seattle sometimes includes the third largest city, which is Tacoma.
St. Louis is the second largest city in Missouri. The largest city is Kansas City. The third largest city is Springfield.