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Alcohol is permeable to many areas of the brain.

However, the main areas affected are:

1) the neocortex - alcohol inhibits activity in the neocortex, responsible for higher-level thinking and execution;

2) the hippocampus - by inhibiting NMDA receptors and increasing GABA-A receptor activity in this region, memory impairment results. In high enough doses, even blackouts can occur, whereby short-term to long-term memory consolidation has been effectively blocked altogether;

3) the cerebellum - inhibiting this region, primarily via GABA-A receptor modulation, reduces fine movement abilities, posture, coordination, etc..;

4) osmoreceptors in the hypothalamus - this results in poor modulation of ADH (antidiuretic hormone), resulting in increased urination and poor water retention, leading to dehydration;

5) in high enough doses, even the lowest regions of the brain can be affected, leading to unconsciousness, coma, or death

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10y ago
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13y ago

Excess consumption of alcohol causes damages to many of the body's organs. Addiction often comes before the physical effects.

Prolonged heavy drinking can seriously affect the brain, liver, stomach, bones, heart, kidneys, and possibly lungs.

The brain may be affected causing confusion and memory loss. The peripheral nerves may be damaged causing changes in sensation and numbness.

The liver's function is to break down the alcohol, but prolonged excess can cause scarring of the liver called cirrhosis.

It may also cause disease of the pancreas and inflammation of the stomach. In some patients it may predispose to stomach cancer.

Excess alcohol can produce heart irregularities and weakening of the muscle of the heart wall. It can also upset the body's natural control of blood fats and blood sugar levels.

Prolonged alcohol may also have an effect on the bones causing bone thinning called osteoporosis and reduce the production of blood cells.

It also can deterioate the kidneys. The vessels of Kidneys lose elasticity and power of contraction.

Alcohol can also cause lung congestion. Alcohol relaxes the vessels of the lungs easily as they are most exposed to the fluctuations of heat and cold. When subjected to the effects of a rapid variation in atmospheric temperature, they get readily congested. During severe winter seasons, the suddenly fatal congestions of lungs easily affects an alcoholic.

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10y ago

Liver is affected by long term consumption of alcohol. Long term alcohol consumption leads to cirrhosis of liver.

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14y ago

alcohol mainly affects the stomach

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13y ago

the brain, heart, and kidneys

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11y ago

The stomach,brain,and liver.

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14y ago

The liver

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8y ago

The brain.

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Q: Which part of the body is most affected by alcohol?
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