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Who discovered hyperkalemic periodic paralysis?

Updated: 9/17/2019
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Q: Who discovered hyperkalemic periodic paralysis?
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What is another name for hyperkalemic periodic paralysis?

Hyperkalemic PP is also called potassium-sensitive PP.


What is hyperkalemic periodic paralysis?

The level of potassium in the blood rises slightly or is normal.


How does the gene for hyperkalemic periodic paralysis present?

The gene for hyperkalemic PP affects virtually all who inherit it, with no difference in male-vs.-female expression.


What gender has a greater genetic risk for hyperkalemic periodic paralysis?

The gene for hyperkalemic PP affects virtually all who inherit it, with no difference in male-vs.-female expression.


How do you describe periodic paralysis?

Periodic paralysis disorders are genetic disorders that affect muscle strength. There are two major forms, hypokalemic and hyperkalemic, each caused by defects in different genes.


What is a Challenge test for hyperkalemic periodic paralysis?

An attack of hyperkalemic PP can be induced with administration of potassium after exercise during fasting. These tests are potentially hazardous and require careful monitoring.


What are the different types of periodic paralysis?

There are two major forms, hypokalemic and hyperkalemic, each caused by defects in different genes.


What is the difference between hypokalemic and hyperkalemic periodic paralysis?

In hypokalemic PP, the level of potassium in the blood falls in the early stages of a paralytic attack, while in hyperkalemic PP, it rises slightly or is normal.


What is the method of treatment for hyperkalemic periodic paralysis?

Attacks requiring treatment are much less common in hyperkalemic PP. Glucose and insulin may be prescribed. Eating carbohydrates may also relieve attacks.


What part of the body is affected by hyperkalemic periodic paralysis?

Weakness usually progresses from the lower limbs to the upper, and may involve the facial muscles as well.


What does the normal gene responsible for hyperkalemic periodic paralysis responsible for?

The normal gene is responsible for a muscle protein controlling the flow of sodium during muscle contraction.


What brings on the attacks of hyperkalemic periodic paralysis?

Missing a meal, with high potassium intake, or use of glucocorticoid drugs such as prednisone. (Glucocorticoids are a group of steroids that regulate metabolism and affect muscle tone.)