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Hyperkalemic PP is also called potassium-sensitive PP.
The level of potassium in the blood rises slightly or is normal.
The gene for hyperkalemic PP affects virtually all who inherit it, with no difference in male-vs.-female expression.
The gene for hyperkalemic PP affects virtually all who inherit it, with no difference in male-vs.-female expression.
Periodic paralysis disorders are genetic disorders that affect muscle strength. There are two major forms, hypokalemic and hyperkalemic, each caused by defects in different genes.
An attack of hyperkalemic PP can be induced with administration of potassium after exercise during fasting. These tests are potentially hazardous and require careful monitoring.
There are two major forms, hypokalemic and hyperkalemic, each caused by defects in different genes.
In hypokalemic PP, the level of potassium in the blood falls in the early stages of a paralytic attack, while in hyperkalemic PP, it rises slightly or is normal.
Attacks requiring treatment are much less common in hyperkalemic PP. Glucose and insulin may be prescribed. Eating carbohydrates may also relieve attacks.
Weakness usually progresses from the lower limbs to the upper, and may involve the facial muscles as well.
The normal gene is responsible for a muscle protein controlling the flow of sodium during muscle contraction.
Missing a meal, with high potassium intake, or use of glucocorticoid drugs such as prednisone. (Glucocorticoids are a group of steroids that regulate metabolism and affect muscle tone.)