Who were the Fab Five?
* The members of 1980s pop band Duran Duran:
Simon Le Bon, Nick Rhodes, John Taylor, Andy Taylor, and Roger Taylor
* The starters on the University of Michigan men's basketball team that played in the NCAA championship game as freshmen in 1992 and again as sophomores in 1993, losing both times:
Chris Webber, Jalen Rose, Juwan Howard, Jimmy King, Ray Jackson
* The rap crew "The Fab 5", founded in 1995:
Rock, Ruck, Starang Wondah, Louieville Sluggah, and Top Dog
* The five midfielders for Australian Football League club Brisbane Lions in 2001, 2002 and 2003:
Michael Voss, Nigel Lappin, Simon Black, Jason Akermanis, Luke Power
* The hosts of the television show Queer Eye for the Straight Guy, launched in 2003:
Ted Allen, Kyan Douglas, Thom Filicia, Carson Kressley, and Jai Rodriguez
* The Fabulous Five (who predated the Beatles by more than a decade) were the starting players on the University of Kentucky men's basketball team that won the 1948 NCAA championship, as well as the gold medal in 1948 Olympic basketball:
Alex Groza, Ralph Beard, Kenny Rollins, Wallace "Wah Wah" Jones, Cliff Barker
* The Hibs Famous Five was a group of forwards who played football for Edinburgh's Hibernian from 1949 to 1955:
Gordon Smith, Bobby Johnstone, Lawrie Reilly, Eddie Turnbull, Willie Ormond
* The Thad Five is the highly touted 2006-07 men's basketball recruiting class at Ohio State University. It is named after OSU head coach Thad Matta:
Greg Oden, Daequan Cook, Mike Conley Jr., David Lighty and Othello Hunter.
Short answer: Just a few amino acids... Better answer: Antibodies are Y-shaped glycoproteins. The two arms are the antigen-binding fragments (Fab) while the base is the crystalizable fragment (Fc). Fab and Fc are linked by the hinge region. Fab and Fab' are generated by proteolytic cleavage of whole antibodies. Papain cleaves antibodies in the hinge region N-terminal to the interheavy chain disulfide bonds leaving two Fab and a Fc. Pepsin cleave C-terminal to the first…
In my opinion, the best squad not to win a championship is the 1983 Houston "Phi Slamma Jamma" team with Olajawon and Drexler. The Fab Five deserves credit for being runner-up in back-to-back years, but considering they didn't even manage to win a Big Ten title means they don't belong in the category of best ever not to win the championship.