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They have both hydrophilic and hydrophobic heads. In a lipid bilayer, the hydrophilic head of the phospholipid faces the outside of the membrane while the hydrophobic head faces the the hydrophobic head of another phospholipid.

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13y ago
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6y ago

They have amphiphilic (both) characteristic. The structure of the phospholipid molecule generally consists of two hydrophobic fatty acid "tails" and a hydrophilic "head" consisting of a phosphate group.

Phospholipids are arranged so that their hydrophobic heads are pointing outwards and their hydrophilic tails are pointing inwards when in a water environment in water. This arrangement allows plasma membranes to be selectively permeable to solutes such as proteins, ions and water.

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Q: Why is a phospholipid both hydrophilic and hydrophobic?
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