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Enzymes act only on a specific substrate due to the active site of the enzymes fits perfectly with the substrate. Like 2 puzzle pieces, they can only go together and not with anything else.

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Marianne Hagenes

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Q: Why do enzymes generally only bind to one type of substrate?
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Why do enzymes generally bind to only type of substrate?

Enzymes act only on a specific substrate due to the active site of the enzymes fits perfectly with the substrate. Like 2 puzzle pieces, they can only go together and not with anything else.


Substrate molecules bind to enzymes where?

The bind in the active site.


Why will only certain substrate molecules fit into the active site?

It will only bind with the enzymes active site of the shapes are complimentary and enzymes are very specific


Why do enzymes usually only work on one substrate (or group of closely related substrates)?

Only certain molecules can fit into the active site of the enzyme.


If Pectinase only breaks down pectin and It has no effect in cellulose What term is used to describe this characteristic of enzymes?

Enzymes are substrate specific; meaning that their active site only allows for a certain substrate to bind - in this case, pectin, and the enzyme has no effect on any other biological molecules


Why must a molecule have a specific shape if it is to be a substrate of an enzyme?

Active sites of enzymes (where the substrates fit in) are substrate specific, and are complementary to the shape of the molecule (substrate). In this way, enzymes can only act on a specific substrate, since that is the only shape that it will accommodate in the active site.


Are Enzymes specific to particular molecules?

Enzymes are proteins that catalyse (speed up) a reaction. They are very specific; enzymes will only bind a very specific molecule (or molecules containing a very specific chemical group). They normally have no effect on molecules that are not their substrate (the specific type of molecule they can interact with). Enzymes work because they have a specific shape and an 'active site'. The active site is the part of the enzyme that will bind its substrate and it may be charged in specific places so that it attracts and binds tightly to the substrate. Because the active site is the right shape and charge for the substrate, it can bind it efficiently and when it does this it causes the enzyme to change shape and catalyse a chemical reaction. Other molecules that are the wrong size, shape or charge will simply not fit into the active site or will be repelled, so the enzyme doesn't affect them. Some enzymes contain complex metal ions at their active site which help create the right conditions to bind the substrate, by adding a certain charge in a certain place. Enzymes can be 'fooled' by molecules of a very similar size, shape and charge as their normal substrate. Many toxins work in this way, by being similar to a certain molecule that the enzyme normally binds to. The toxins cause a problem because they are slightly different from the actual substrate and so don't react but just occupy the active site permanently or until they fall out. This means that the enzyme is useless.


What happens to the enzyme after the substrate is changed?

enzyme works as a catalyst before and after the reaction it is preserved


Can The activation site of an enzyme bind to a specific subtrate?

The activation site of an enzyme can only bind to a specific substrate.


Is substrate bind to the enzyme by collision?

Collision only introduces the substrate to the active site. Binding is usually hydrogen bonding.


What is the name of an enzyme only acts on one substrate?

Most enzymes are substrate specific because they have a specific shapes active site in which only a specific substrate can fit.


Do enzymes work only on single substrate in most cases?

Yes, almost all work on a single substrate.