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Why is it that an Rh-negative person does not have a transfusion reaction on the first exposure to Rh-positive blood but does have a reaction on the second exposure?
Wiki User
∙ 14y ago
Because antibodies that cause the reaction are not naturally occurring. One has to be exposed to Rh in order to make antibodies to it. Its the same process as the reaction to a vaccine. The vaccine exposes you to an antigen and your body learns how to react to it in order to protect you from it. If you are exposed to the Rh factor, your body learns how to react to it, and so the next time you're exposed, the reaction is greater.
The major blood groups are different. The antibodies occur naturally. A group O person typically has antibodies to blood from group A and group B donors. Whereas a group AB person doesn't have these antibodies.
Also, there are lesser known antigen/antibody groups that can cause trouble. That's what makes my job in the Blood Bank more interesting.
Wiki User
∙ 14y ago
Wiki User
∙ 14y agobecause it takes time for the body to react and start making antibodies
Wiki User
∙ 12y agoBecause the RH-negative person does not have anti-RH antibodies occurring naturally in their bodies. They only produce the antibodies after the first exposure to RH-positive blood.
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Is a serious and potentially fatal complication that occurs when the patient's blood and the donated blood do not match?
Acute immune hemolytic reaction
What are the risks associated with receiving a blood transfusion?
Sometimes problems occur with a blood transfusion, but that is supposed to be rare. Some people can have an allergic reaction to the transfusion.
What risks for a recipient in a blood transfusion are there?
The blood given by transfusion must be matched with the recipient's blood type. Incompatible blood types can cause a serious adverse reaction (transfusion reaction). Blood is introduced slowly by gravity flow directly into the veins
Why collect a urinalysis after a blood transfusion reaction?
monitor the treatment
Why is medication not allowed to be infused into the blood transfusion set while a blood transfusion is going on?
Every blood transfusion carries the risk of allergic reaction, to anaphylactic shock, even if blood type is perfectly matched. If medication was also infused along with the blood, and the patient had an allergic reaction, it would be impossible to tell which sustance was causing the reaction: the blood? or the medication? Remember that every transfusion reaction can be deadly. As well, some meds may break down blood components. Therefore, never inject IV meds into a transfusion tubing or combine medications into a blood transfusion set.
What are the hazards of incompatible blood transfusion?
Risks associated with autologous blood transfusion include transfusion reaction if an allogeneic blood transfusion was inadvertently given and transmission of infectious agents if the blood became contaminated.
What is the possible cause of death in a blood transfusion?
These complications may include an acute hemolytic transfusion reaction (AHTR), which is most commonly caused by ABO incompatibility. The patient may complain of pain, difficult breathing, fever and chills, facial flushing, and nausea.
In a transfusion reaction the hemolysis of mismatched erythrocytes results from what?
Complement Fixation
What does adverse transfusion event mean?
"Adverse" means harmful or unfavorable, and transfusion probably refers to blood transfusion--so a negative reaction to a blood transfusion? The term is very vague; without context it's hard to say exactly what this would mean.
Which antibody capabilities causes a transfusion reaction with A or B erythrocyte antigens?
Agglutination
Is a transfusion reaction a subacute hypersensitivity to foreign red blood cells?
True.
What is the most common reaction to blood transfusions?
An acute febrile reaction is the most common adverse reaction to a blood transfusion. This is typically treated with tylenol.
