answersLogoWhite

0


Best Answer

An enzyme's ability to function comes from its shape, which is a result of the folding of the amino acid chain that it's made of. Enzymes act on their substrates (just a fancy word for whatever molecule or chemical or anything that an enzyme acts on) on a certain part of the enzyme called the active site. This can be modeled by an example such as a lock and a key. The lock would be the enzyme, and the key the substrate. It's a very specific fit. When an enzyme becomes denatured, it starts to unfold, which changes its shape. Changing the shape of the active site, means that the substrate no longer fits, just as the key would no longer fit if you heated the lock until it melted. Since the substrate can no longer bind to the enzyme's active site, the enzyme is no longer effective.

User Avatar

Wiki User

15y ago
This answer is:
User Avatar
More answers
User Avatar

Wiki User

12y ago

Denatured enzymes will not function because its active site has been permanently deformed. It is this region where the substrate specific to that enzyme fits, in order to be built up/ broken down into new products. Once the enzyme's structure has been misshapen, whether by unsuitable temperature or pH, no further reactions can be carried out by the enzymes.

This answer is:
User Avatar

User Avatar

Wiki User

12y ago

When an enzyme is denatured the active sites of the enzyme change shape (often because the enzyme is out of its tolerated ranges) the substrates are then unable to fit perfectly, as needed to complete the process. Therefor when an enzyme is denatured, it cannot function properly and complete its process

This answer is:
User Avatar

User Avatar

Wiki User

13y ago

Their shape is disfigured, so to say, and the substrate will no longer fit "like a puzzle."

This answer is:
User Avatar

User Avatar

Wiki User

13y ago

by heating

This answer is:
User Avatar

Add your answer:

Earn +20 pts
Q: Why do denatured enzymes become disfunctional?
Write your answer...
Submit
Still have questions?
magnify glass
imp
Related questions

What is protein denatured by?

A denatured protein has had its structure dismantled or altered, rendering it disfunctional or nonfunctional, and therefore useless.


If enzymes do not function they are called?

Enzymes that become no longer functional are referred to as being "denatured".


Denatured enzymes are the same as?

Denatured enzymes are the same as enzymes that can no longer function.


How does acid rain affect enzyme activity?

The enzymes become denatured


What is the name for an enzyme that has lost its ability?

No, enzymes stop working when the body dies


What happens if enzymes are not at optimum ph?

Enzyme become denatured.


At which temperature do most enzymes from the human body become completeley denatured?

40 degrees


If your body temperature is low how will the enzymes work?

Enzymes require certain temperatures to function. They become denatured if the temperature is too high or too low. If an enzyme is denatured, it can no longer function. Therefore, if your body temperature is too low, the enzymes will become denatured and cease to function. The process of denaturation is on a continuum, however. If the temperature is slightly lower than normal, but not too low, the enzymes will still function, but at a lower rate.


What would the reaction be in the enzymes if the PH of the stomach was doubled?

The enzymes would become denatured because the PH would be too acid/alkaline (depending which way you double) for them to work properly. Denatured basically means that they would be worn down by the acid, and become mishapen.


What happens to enzymes in your body whenever your run fever?

Enzymes can not function well at higher tempatures so they become denatured and their body functions are not able to stay normal.


What could happen if an animal's enzymes overheat in a desert climate?

The enzymes will become denatured and not work. All metabolic processes would shut down. They may die.


What can be denatured by changes in temperature or pH?

enzymes