Will photoshop.com give you a virus?

The photoshop.com domain is owned by Adobe, the makers of the Photoshop progam. It's rather unlikely, though not strictly speaking impossible, that you could get a virus from there.

If you've gotten a "photoshop.com" file from somewhere, I would be extremely suspicious of it, and wouldn't at all be surprised if it contains viruses or is a Trojan horse designed to do nasty things to your computer.