No, it would cause the engine to run poorly but not to seize. Lack of lubrication or overheating will cause that. Also a broken part, as in a rod, will cause it to seize.
Engine missfire. Cylinder #4
There is likely a crack in the engine block.
engine coolant getting into an engine cylinder from a bad head gasket , cracked or warped head
Wiring and internal engine problems can cause misfires.
If the vacuum hose connected to the PCV valve was disconnected, it would idle poorly if at all, otherwise, no.
The catalytic converter
Bad Plug or coil pack.
Definitely. The converter becomes plugged and the engine can't breathe [exhale].
Anything that could cause a cylinder misfire can cause the check engine light to flash. A restricted fuel filter is one.Anything that could cause a cylinder misfire can cause the check engine light to flash. A restricted fuel filter is one.
If you have a "check engine" light on, start with having the codes read. A misfire code can tell you which cylinder or cylinders are having problems. A misfire could be the cause of your engine vibration.