Atticus tells Scout that most people are, in the end, good or nice people. This is in response to Scout's wonderings about Boo Radley and his different/reclusive nature.
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Atticus is referring to the idea that most people have good intentions and are inherently kind when given the chance to truly know them and understand their perspective. The line serves as a reminder to Scout that empathy and understanding can help bridge gaps between people and foster a sense of compassion and respect.