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The precise manner in which an enzyme lowers the activation energy of a reaction is not known, but current ideas are contained in the "induced-fit model" of enzyme action.

This model (or idea) suggests that when an enzyme and substrate (we'll consider a single substrate, but there may be more than one) interact to form an enzyme-substrate complex, the active site of the enzyme alters shape somewhat, and in so doing puts strain on bonds of the substrate molecule.

The resultant form of the substrate requires less energy than a free substrate molecule to reach the transition state, which is the form of the molecule at the peak of the graphical plot of free energy against time.

The chemical nature of the particular amino acids that form the boundaries of the active site is critical to the process, as the side-chains of these amino acids interact with the substrate.

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โˆ™ 2008-09-26 09:14:13
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Q: How does an enzyme lower the activation energy of a reaction?
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Related questions

Does an enzyme lower the activation energy of a reaction?

The definition of enzyme is a macromolecule of protein that lowers the activation energy of a chemical reaction.


What does an enzyme do to activation energy?

Enzymes generally lower the activation energy of a reaction, making them easier to take place.


Difference between catalyzed and uncatalyzed reactions?

Catalyzed reaction has a lower activation energy because there is an enzyme present in the reaction. Uncatalyzed reaction has a higher activation energy because there is no enzyme present in the reaction.


What can speed up a reaction or lower the activation energy of a reaction and can digest things?

This would be an enzyme.


How enzyme accelerate metabolic reaction?

Enzymes lower the activation energy required to start the reaction.


What substance helps a chemical reaction?

A catalyst. Or, an enzyme can lower the activation energy of a chemical reaction.


How does an enzyme affect he activation energy of a reaction?

Enzymes lower the activation energy so the reaction can take place at a lower activation temperature/energy. -Im an AP/College Biology student. Trust me on this lol


Can an enzyme make an endothermic reaction exothermic?

Some enzymes can lower the activation energy of the reaction to that extent.


What happens to an enzyme during a biochemical reaction?

During a biochemical reaction, an enzyme binds with a substrate to lower the activation energy of the reaction. This results to an increase in the reaction rate.


What does an enzyme lower the energy of?

Activation energy (Ea)


How does an enzyme catalyze a chemical reaction in regards to activation energy?

Any catalyst will make a chemical reaction easier or quicker to happen by lowering the activation energy. On a energy diagram, you will see a lower "hill" for activation energy, which corresponds to less energy required to begin the reaction.


What affect rates does a enzyme catalyzed reaction have?

Enzymes increase the rate of reaction by changing the reaction mechanism to one with a lower activation energy.

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