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What type of mutation is the most significant effect on protein synthesis?
Wiki User
∙ 11y ago
Mutations change the order in which the organic bases are in your DNA. These bases code for proteins, and if they change, so the code changes. A change in the code can mean a different protein is made or that proteins are not made at all. The way it could stop proteins from being made is that the change could create a Stop Codon, which stops mRNA from being translated (which would then be transcribed into proteins). If it forms a Start Codon, then the wrong section of DNA could be translated and the wrong proteins be synthesised.
There is not always a change in to proteins synthesised, as for each amino acid in a protein there is more than one code. A mutation could change the code for a protein into a different code, but for the same protein. In such a case there would be no change.
Wiki User
∙ 14y ago
Wiki User
∙ 10y agoThe type of mutation that cause the greatest change in the final protein is dependent upon the type of test. Mutations can be very different depending upon the test parameters.
Wiki User
∙ 11y agoFrameshift mutation
Wiki User
∙ 12y agoFrame Shift Mutation
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What is a mutation called that has no effect on an organism?
A point mutation, in which one nitrogen base in a codon is substituted for another, may have no effect on an organism. This is true if the base substitution does not change the amino acid that the codon represents, or if the mutation occurs in a non-critical location in the protein so that the protein's structure is not changed significantly and the protein is still able to function.
If one of the nitrogen bases were replaced by a different base what effect might that have on protein synthesis?
It depends. Because many amino acids have more than one codon, it may not affect the protein at all. However, if it does change the amino acid sequence, it could cause a change in the three-dimensional structure of the protein, resulting in a mutation.
What is a possible effect on an error during transcription?
A possible effect on an error during transcription is that a nonfunctioning protein will be produced. The protein would be made of the wrong amino acids chain will be produced (and wrong shape). The wrong protein will be produced. the wrong amino acid chain will be produced
Does this mutation affect the protein produced?
Mutations in DNA cause an incorrect amino acid to be used when assembling the protein. If the protein is complex, the mutation will cause a subtle failure in the process that the mutation affects. Errors in proteins due to mutations either lead to death or to a disruption of control paths, which causes illness and loss of function. But a mutation in the DNA doesn't necesarily make a difference, as more than one DNA sequence codes for the same amino acids, and if that is the case before and after the mutation, it wouldn't have any effect. However mutations can also be a good thing, as it can randomly generate a positive effect, like making enzymes for processing grass, this is the theory behind evolution
Does alteration of DNA cause cell death?
It will depend on how the DNA is altered. If the introns are altered there should be no significant risk to the cell. If a single base is altered, but the codon still produces the same amino acid (silent mutation) - there will be no effect on cell function. A major change to DNA (such as a frame-shift or nonsense mutation) may affect vital protein products and this could lead to cell death.
What does a point mutation cause?
A point mutation is when a single nucleotide switches from G to C or from A to T, or when a single nucleotide is deleted or inserted. It's unlikely for any single mutation to have a significant effect, but the effects that could occur could be anything, ranging from eliminating or altering protein synthesis of a particular protein to altering the regulatory function of a stretch of DNA and thereby affecting the embryological development of an organism.
How is it possible for a point mutation to have no effect on the function of gene?
If the point mutation does not change the protein to be translated in the 3-letter sequence, then it will have no effect on the gene's function.
What is a mutation called that has no effect on an organism?
A point mutation, in which one nitrogen base in a codon is substituted for another, may have no effect on an organism. This is true if the base substitution does not change the amino acid that the codon represents, or if the mutation occurs in a non-critical location in the protein so that the protein's structure is not changed significantly and the protein is still able to function.
If one of the nitrogen bases were replaced by a different base what effect might that have on protein synthesis?
It depends. Because many amino acids have more than one codon, it may not affect the protein at all. However, if it does change the amino acid sequence, it could cause a change in the three-dimensional structure of the protein, resulting in a mutation.
If the ribosomes of a cell were destroyed what effect would this most likely have on the cell?
It wouldn't be protein synthesis.
How a point mutation can effect the overall protein shape and function using hemoglobin as an example?
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What effect does aging have on skeletal muscles?
loss of bone mass from demineralization and brittleness from a decreased rate of protein synthesis
What is a possible effect on an error during transcription?
A possible effect on an error during transcription is that a nonfunctioning protein will be produced. The protein would be made of the wrong amino acids chain will be produced (and wrong shape). The wrong protein will be produced. the wrong amino acid chain will be produced
What will happen if there was a change in the base pair sequence?
Changing a base pair on a human chromosome (or any organism's chromosome) can range from no effect to catastrophic. The changing of a base pair -- a mutation -- can either result in a nonsense mutation, a missense mutation, or a silent mutation.A nonsense mutation changes a codon upstream of the normal stop codon into a stop codon, resulting in a truncated protein. Such proteins are non-functional and usually result in a non-viable offspring although some can survive (with serious genetic disorders).A missense mutation is just like a nonsense mutation, except the codon isn't changed into a stop codon and the protein does not terminate early. The only difference between the normal protein and the affected protein is that the affected protein will have one amino acid along the polypeptide chain that is different. The affects of such a change can change the shape of the protein entirely, seen with sickle-cell anemia.A silent mutation has no effect on the protein produced. There are only 20 amino acids, but 43 variations of four bases arranged three at a time (in other words, there are 64 different codons possible). Accordingly, more than one codon can code for the same amino acid. For example, both UAU and UAC code for the amino acid tyrosine. Imagine a point mutation replaced the U in UAU with a C making it UAC. Either way, the amino acid that will be used will be tyrosine, in no way changing the structure of the protein. For that reason, these mutations are "silent" or having no effect.
Are the number of cell ribosome allows to synthesis thousands of different protein?
The number doesn't effect the types of proteins that a cell produces. The DNA tells the ribosome (in a round about way) what the protein will be.
Explain how a mutation could have no effect on the organism?
It can have absolutely no affect, a bad affect, or even a good affect.*Deletion and Addition are frameshift: most harmful.
Does this mutation affect the protein produced?
Mutations in DNA cause an incorrect amino acid to be used when assembling the protein. If the protein is complex, the mutation will cause a subtle failure in the process that the mutation affects. Errors in proteins due to mutations either lead to death or to a disruption of control paths, which causes illness and loss of function. But a mutation in the DNA doesn't necesarily make a difference, as more than one DNA sequence codes for the same amino acids, and if that is the case before and after the mutation, it wouldn't have any effect. However mutations can also be a good thing, as it can randomly generate a positive effect, like making enzymes for processing grass, this is the theory behind evolution
