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A very severe genetic sickness occurs in about 1 in every 100000 individuals Calculate the frequency of carriers for this recessive disease?
I'll get it started, but this is a complicated question. Assuming this is an autosomal trait, and assuming it only has one gene, and assuming it causes death before reproductive age: In order for someone to develop the phenotype, both parents have to be carriers. So, for the 1 out of 100,000 child born with the disease, you had to have 2 carriers mate. But there were more than 2 carriers in the 100,000. How many carriers do you have to have for 2 of them to mate? For that, you'd have to know how many people out of a population of 100,000 actually mate in the first place. You'd also have to know the average number of children resulting from a union. Let's say 75% of people mate, and the average number of children is 2. So of 100 people, 75 mate. But each union involves 2 people, so there are actually 37.5 pairings, producing 37.5 x 2 = 75 children. Now, assuming a frequency of carriers of F, what is the likelihood of 2 carriers mating? Let's say that everybody mates. So out of 100 people, there are 50 pairings. So the probability of mating with a carrier is approximately F.
What else can I help you with?
Why are most genetic defects related to enzyme function recessive disorders?
Most genetic defects related to enzyme function are recessive because most are lethal and can only persist because heterozygote carriers can live to reproduce.
What kind of diseases are the most common genetic diseases For example those in which both parents may be carriers of the disease without knowing it because they don't actually have the disease?
What kind of diseases are the most common genetic diseases? (For example, those in which both parents may be carriers of the disease without knowing it because they don't actually have the disease.)
What is the voltage wave form?
It is positive and negative signal in the frequency of wave form, the voltage of amplitude modulation, that carriers the signal of frequency.In the process of graph showing result ...
Difference between an autosomal recessive disorder and an autosomal dominant disorder?
autosomal dominant is only when one allele is messed upautosomal recessive is when you give the disease to your child 50/50 chance.Not true.... 50/50 when its Autosomal Dominant(see below)Recessive InheritanceBoth parents carry a normal gene (N), and a faulty, recessive, gene (n). The parents, although carriers, are unaffected by the faulty gene. Their offspring are affected, not affected, or carriers. This type of inheritance was first shown by Mendel.Dominant InheritanceOne parent has a single, faulty dominant gene (D), which overpowers its normal counterpart (d), affecting that parent. When the affected parent mates with an unaffected and non-carrier mate (dd), the offspring are either affected or not affected, but they are not carriers.
Does inbreeding increase genetic variation?
Many negative diseases and traits are very rare and recessive. In a population where very little inbreeding occurs, these negative traits do not show up frequently because such a small percent of the population is a carrier for them. When related individuals who are carriers of these negative recessive traits breed with each other, their offspring receive two copies of the trait, resulting in the physical or mental retardation of the offspring due to the negative trait.
Can you provide some examples of Hardy-Weinberg practice problems for me to work on?
Here are a few examples of Hardy-Weinberg practice problems for you to try: In a population of 500 individuals, 25 exhibit the recessive trait for a certain gene. What are the frequencies of the dominant and recessive alleles in the population? If the frequency of the homozygous dominant genotype in a population is 0.36, what is the frequency of the heterozygous genotype? If the frequency of the recessive allele in a population is 0.2, what percentage of the population is expected to be carriers of the recessive trait? These problems can help you practice applying the Hardy-Weinberg equilibrium to calculate allele and genotype frequencies in a population.
Why were heterozygous individuals called carriers for non-sex-linked and x-linked recessive patterns of inheritance?
I don't know and don't care
What do half shaded circles mean for pedigrees?
In pedigree charts, half-shaded circles represent individuals who are carriers of a specific genetic trait or disorder but do not express the trait themselves. This typically indicates that the individual has one copy of the recessive allele associated with the trait, while the other copy is dominant. Carriers can pass the recessive allele to their offspring, potentially resulting in affected individuals if both parents are carriers.
Why are heterozygous individuals called carriers for non-sex-linked and X-linked recessive patterns of inheritance?
I don't know and don't care
Why are lethal dominant alleles less common than lethal recessive alleles?
Lethal dominant alleles are less common than lethal recessive alleles because individuals with lethal dominant alleles typically die before they can pass on the harmful gene to their offspring, reducing the frequency of the allele in the population. In contrast, individuals with lethal recessive alleles can carry the gene without showing symptoms, allowing the allele to persist in the population through carriers who can pass it on to their offspring.
How would a recessive trait show up in a cross between two individuals with a dominant phenotype?
In a cross between two individuals with a dominant phenotype but carrying a recessive trait, the recessive trait would not be visibly expressed in the offspring (since they don't inherit two copies of the recessive allele). However, they would be carriers of the recessive trait, meaning they could pass it on to future generations.
Why is it possible that a majority of people may display a recessive trait?
It is possible for many people to display a recessive trait because the people have two recessive genes. Dominant simply means it will trump a recessive gene, it does not mean it is the most widely seen gene in a species.
How is a recessive trait in a pedigree?
In a pedigree, a recessive trait is typically represented by filled-in shapes (squares for males and circles for females) to indicate individuals who express the trait. A recessive trait appears in an individual only if they inherit two copies of the recessive allele, one from each parent. Consequently, unaffected parents can have affected offspring if both are carriers of the recessive allele. The pattern often shows skipped generations, as the trait can be passed through carriers without manifesting.
Which gender has a higher frequency of sex linked traits?
Males typically have a higher frequency of sex-linked traits because they have only one X chromosome, making recessive sex-linked traits more likely to be expressed. Females have two X chromosomes and can be carriers of recessive sex-linked traits without showing the phenotype.
Is sickle cell an dominant or recessive?
Sickle cell anemia is an autosomal recessive disorder. It can result from two carriers having a child together.
What is the frequency of carriers of albinism in the population?
12
Most copies of harmful recessive alleles are carried by?
Most copies of harmful recessive alleles are carried by unaffected carriers who are phenotypically normal but carry one copy of the allele. When two carriers have offspring, there is a 25% chance the child will inherit two copies of the harmful allele, leading to a genetic disorder.
