1850 - the Fugitive Slave Act, which was meant to show support for the legality of slavery, but which backfired on them, causing Harriet Beecher Stowe to write 'Uncle Tom's Cabin' as a protest.
1854 - the chance of new slave-states, if the people of each state were willing to vote for slavery.
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the kansas nebraska act, of the compromise of 1850
The Missouri Compromise The Compromise of 1850 The Kansas-Nebraska Act.
Respectively, Henry Clay and Stephen Douglas.
The Missouri Compromise of 1850 affected Kansas & Nebraska territories. The Compromise was an extension of the one made in 1820. The idea behind the compromises was to maintain the balance of free states and slave states. Now the statehood of Kansas & Nebraska came into the mix. The consensus of Congress was that left to themselves, the people of Kansas would follow the lead of Missouri and vote to become a slave state. Also, that the people of Nebraska would vote for a "free state". Later events, such as a major conflict in Kansas & the soon to come Civil War would send the compromises into a free fall.
The line of the Missouri Compromise - North of that line, slavery was illegal. The Compromise of 1850 made some new provisions about the territories acquired from Mexico, but this did not secure lasting agreement. That was why Stephen Douglas proposed the Kansas-Nebraska Act, allowing the people of each new state to vote whether to be slave or free.