Results for: loss-of-heterozygosity

What is Loss of heterozygosity?

LOH stands for Loss of Heterozygosity. LOH happens when a somatic cell consist only of one copy of allele caused by non-disjunction in mitosis, segregation all through out re-combination, or during chromosome segment deletion. Full Answer

Human Karyotype-Nomenclature Human genome?

To determine the commonly deleted region on chromosome 3 in carcinoma of the uterine cervix, these samples were also examined for loss of heterozygosity at 5 other loci on chro mosome 3: RAFl(3p24-25) (14); ERBAß(3p22-24.l ) (17); DNF15S2 (3p21) (13)… Full Answer