Hemophilia

A haematologist does. As blood diseases are not that common, you are not guaranteed to find one in your direct environment. Your general MD will transfer you when needed.

You would get it from your mother. It is a sex-liked genetic disorder.

Females are the carriers, males exhibit the condition.

Hemophilia is invisible except when the afflicted person is bleeding, then it is visible in terms of prolonged bleeding, beyond the point when a normal person would have stopped bleeding.

Yes. In order to develop Tay-Sachs, you must inherit the gene for it from BOTH parents. If you inherit from ONE parent, you can be a carrier, but will not develop the disease. If BOTH parents are carriers, your odds of inheriting Tay-Sachs is 1-4. Other genetic diseases, such as Huntingtons, are carried on a dominant gene- If one parent has gene, odds are 1-2. Link at the bottom of the page for more information on Tay-Sachs:

Partly true, but the girls carry the disease, they usually don"t have it. Hemophilia among women is rare, but does occur. We were so close there was no room, but Only Stacy was immune! ( parody on Melanie song Lay Down) It is obviously about the St. Petersberg massacre.

Approximately 1/3 of the cases of hemophilia are results of random mutations at the time of conception. Thus it is really not that uncommon for two people with completely standard genetics to have a child with hemophilia.

Another possibility is that the mother was a carrier and didn't know. Since Hemophilia is due to a mutation on the X chromosome and females have two X chromosomes, it is possible for her to have no signs or reason to believe that she is a carrier. Even in cases with no family history prior, the spontaneous mutation can effect one of the mother's X chromosomes and then get passed on without her knowing she was a carrier.

The simple answer is - you can't ! Hemophilia is a genetic medical condition - not a communicable disease. A person is born with the disease. You can't 'catch' it from being in contact with someone - nor is it spread by the person touching surfaces etc. It is treatable - but incurable. A person with Hemophilia has it all their life.

Abraham Lincoln had hemophilia, along with Mother Theresa and Ghengis Khan, the Owners of Walmart in DesAllemands, and Alexi Romanov, Anastasia's brother

"X-linked" disorders are more commonly observed in males do to the chromosomal make up of boys and girls. As you are probably already aware, females have two X chromosomes and no Y chromosomes. Males on the other hand have one Y chromosome and only one X chromosome.

Since this is the case, when a male receives an X chromosome with a mutation on it, they have to use that X chromosome as a "blueprint" even if the information on it is wrong. When a female has a mutation on one of her X chromosomes, she typically has another non-mutated X chromosome from which she can get the correct information.

Hemophilia in the US is considered rare. Affecting mostly males, it occurs in about 13 of every 100,000 people.

I'm not sure where he is getting his data from, however;

I've heard the number 1/10,000 used many times, however there is no single source of data that does not contradict itself.

According to the US Census Bureau the Population of the United States in 2011 was estimated to be 311, 591,917. According to the Centers for Disease Control, there are only an estimated 20,000 males with hemophilia in the United States and considerably fewer females. If we do the math, we see that 311,591,917 / 20,000 says that there is approximately 1 male with hemophilia for every 15,580 people. This means 10 males in approximately 155,800 people.

If we also include the females into these numbers (for which there is very few females, definitely less than 1 female for every 10 males) we would see at most 11 hemophiliacs (both male & female) / 155,800 people which is equivalent to about 7 in 100,000 people.

The strongest source of data really comes from males born with hemophilia each year. According to the CDC, there are approximately 400 male hemophiliacs born each year wich equates to 1/5000 male births. However we must remember the lower than average age of death that lowers this ratio significantly when looking at the population as a whole. In 20 or 30 more years, this will probably become the default ratio as the health care and safety of medications now offer people with hemophilia near normal life expectancies.

Hemophilia has several common symptoms and these include bleeding of the joints and muscles, and prolonged bleeding. Bleeding is not typically faster or different to someone without hemophilia but it takes much longer to stop, typically, and this is the main symptom of the illness.

Well, due to thin blood, they would have to only eat raw eggs for meals and only sleep for an hour a day. They call me Queen Amidala.

Hemophilia is passed down from mother to son. It is extremely

rare for a woman to have hemophilia. It is necessary, though, for

a woman to be a carrier of the disorder for her son to acquire this

disorder. Females have two X chromosomes whereas males only

have one. When a boy is born, he takes one X chromosome from

his mother and one Y chromosome from his father. Therefore, he

can only get hemophilia through his mother.

Example One:

Mother(Carrier)+Father(Non-Affected)=50% chance of their son

acquiring the disorder and 50% chance of their daughter being a

carrier.

Example Two:

Mother(Non-Affected)+Father(Hemophiliac)=All sons will be

non-affected and all daughters will be carriers.

Hemophilia

this disease is caused by a recessive allele that is found only on the x chromosome. a human female has two x chromosomes. a human male only has 1 x chromosome. therefore, a male needs only one recessives allele to have hemophilia, while a female needs two recessive allele. as a result, hemophilia is much more common in males.

Hemophilia is passed down from mother to son. It is extremely

rare for a woman to have hemophilia. It is necessary, though, for

a woman to be a carrier of the disorder for her son to acquire this

disorder. Females have two X chromosomes whereas males only

have one. When a boy is born, he takes one X chromosome from

his mother and one Y chromosome from his father. Therefore, he

can only get hemophilia through his mother.

Example One:

Mother(Carrier)+Father(Non-Affected)=50% chance of their son

acquiring the disorder and 50% chance of their daughter being a

carrier.

Example Two:

Mother(Non-Affected)+Father(Hemophiliac)=All sons will be

non-affected and all daughters will be carriers.

The answer to this question is not cut and dry. Literally speaking, a person with hemophilia does not bleed easier than any other person. Hemophilia slows the blood's ability to clot and thus a person with hemophilia will bleed longer than other people.

The perception that people with hemophilia bleed easier comes from two situations.

First, minor trauma such as bumping into something does the same damage to both individuals (those with and without hemophilia), however the individual without the bleeding disorder may plug damaged blood vessels with clots so fast that the injury leads to no noticeable damage. A person with hemophilia may develop bruising or swelling as a result since the damaged blood vessels leak for a longer period of time.

Second, the damage done to joints and tissue from prolonged bleeding can make the area more susceptible to future trauma and more easily injured. In this instance, the individual may "bleed easier", however this is a secondary effect, caused by earlier bleeding, not hemophilia directly.

The X chromosome. That's why it's more common in males; females have 2 X chromosomes, but males only have 1. So if a woman has the hemophilia mutation on one of her chromosomes, she probably won't be affected by it.

• If the father has hemophilia and the mother is a carrier, sons will have a 50% chance of having hemophilia. Daughters will have a 50% chance of having hemophilia and a 50% chance of being a carrier. It is very rare for both parents to have these defective genes.
• If the father does not have hemophilia and the mother is a carrier, sons will have a 50% chance of having hemophilia. Daughters will have a 50% chance of being carriers.
• If the father has hemophilia and the mother has normal blood, all sons will be normal and all daughters will be carriers.

Haemophilia is often spelled with an extra "a" in scientific journals but hemophilia has become widely used.

My favorite is saveonelife.net

There is also hemophilia.org

There are many others as well.

Normally a woman is only a carrier of hemophilia, but if her mother is a carrier and her father has hemophilia the female does have a chance to get it. It is very rare for this to happen but It has been recorded.

Yes, testing the mother for skewed x-inactivation.

If the female has what is classically defined as female hemophilia (carries the mutation on both of her X chromosomes), then all sons she would have would also have hemophilia. All of the woman's daughters would also inherit the gene, however since they would also be getting a normal X chromosome from their father, they would not, themselves, have hemophilia under the classical definition.

Today, it is understood that even carrying the trait on a single X chromosome can reduce a female's factor levels and give cause for doctors to diagnose her with hemophilia. Thus if you are simply looking at genetics (which you probably are) then the answer is all of her sons would have it and all of her daughters would be carriers. Therefore, since there is a 50-50 chance the first child bore would be a male, and a 50-50 chance it would be a female, the chance that their first child born would have hemophilia is 50%.