Karyn Harrison was born in 1961, in Santa Barbara, California,
USA.
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Barbara Jane Harrison, GC was born on 24 May 1945 at the family
home in Kingsdale Crescent, Bradford, Yorkshire to Lena and Alan
Harrison.
A good link is shown below
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Barbara Bush is not related to president William Henry Harrison.
However, her father was a distant cousin of 14th president Franklin
Pierce (both descended from Massachusetts colonist Thomas
Pierce).