Have any players made it to the NFL without going to college?

Yes, people can make the NFL with out playing college football. Vince Papale who played for the American Football League. He played from 1976 through 1978. Also he was the AFL's oldest rookie at 30. During that time, he played in 41 of 44 regular season games (regular seasons being 14 games in 1976-1977 and 16 games in 1978. He later had the movie "Invincible" made after his true story.