Orlando Sanchez debuted on May 6, 1981, playing for the St. Louis Cardinals at Busch Stadium II; he played his final game on May 25, 1984, playing for the Baltimore Orioles at Memorial Stadium.
Orlando Alvarez debuted on September 1, 1973 and played his final game on June 18, 1976.
Orlando Cabrera debuted on September 3, 1997 and played his final game on September 23, 2011.
Orlando Cepeda debuted on April 15, 1958 and played his final game on September 19, 1974.
NFL player Orlando Scandrick played for Boise State.
NFL player Orlando Franklin played for Miami (Fla.).
Alejandro Sanchez debuted on September 6, 1982, playing for the Philadelphia Phillies at Veterans Stadium; he played his final game on May 16, 1987, playing for the Oakland Athletics at Oakland Coliseum.
Anibal Sanchez debuted on June 25, 2006, playing for the Florida Marlins at Dolphin Stadium; he played his final game on September 28, 2013, playing for the Detroit Tigers at Comerica Park.
Felix Sanchez debuted on September 3, 2003, playing for the Chicago Cubs at Wrigley Field; he played his final game on September 20, 2003, playing for the Chicago Cubs at Wrigley Field.
Gaby Sanchez debuted on September 17, 2008, playing for the Florida Marlins at Dolphin Stadium; he played his final game on September 29, 2013, playing for the Pittsburgh Pirates at PNC Park.
Luis Sanchez debuted on April 10, 1981, playing for the California Angels at Anaheim Stadium; he played his final game on October 6, 1985, playing for the California Angels at Anaheim Stadium.
Tony Sanchez debuted on June 23, 2013, playing for the Pittsburgh Pirates at PNC Park; he played his final game on September 29, 2013, playing for the Pittsburgh Pirates at PNC Park.
Orlando Alvarez debuted on September 1, 1973, playing for the at ; he played his final game on June 18, 1976, playing for the California Angels at Anaheim Stadium.