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Bob Friend of the Pittsburgh Pirates. Rose's first MLB hit was a triple off of Friend in the 8th inning of the game played April 13, 1963.
Sammy Sosa was the first batter to hit a home run against every Major league team
Brooks Robinson 4 (Hank Aaron 0)
Although the definition of "major league" has been argued, present day MLB, as well as the Hall of Fame, define the first "major" league as the National League founded in 1876. The link below describes the first game played in that league, on April 22, and mentions that Jim O'Rourke got the first hit in that game.
Pete Rose's first MLB base hit was a triple off of Pittsburgh Pirates righthander Bob Friend on April 13, 1963.
A Pinch hit GRAND SLAM against the Colorado Rockies
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albert pujols of the cardinals record for most home runs hit in is first major league season was 37 homers in 2001
Lou Gehrig hit his first major league home run off of Boston Red Sox pitcher Bill Piercy. It was on September 27, 1923 at Fenway Park.
Yes. In his first major-league at bat against the Houston Astros on April 8, 1986, the San Francisco first baseman hit the first pitch he ever saw for a home run. He hit the homer off future Hall of Fame pitcher Nolan Ryan.
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