Tom Cheney, pitching for the Washington Senators. He struck out 21 Baltimore Orioles in a 16 inning game September 12th 1962.
Buddy Scholtz had 26 strikeouts in a game for Miami University.
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For the Los Angeles Angels single game records, the pitcher with the most strikeouts in one game of nine innings is Nolan Ryan with 19. The pitcher with the most strikeouts in a game with extra innings is also Nolan Ryan with 19. The pitcher with the most strikeouts in one inning is Chuck Finley with 4. The record for most strikeouts in a game by the team is 18. The player with the most strikeouts in one game while batting is Dallas McPherson with 4. The most strikeouts by a batter in a game with extra innings is Billy Cowan with 6.
Sandy Koufax with 382 strikeouts in 1965.
Tom Cheney of the Washington Senators holds the MLB record for most strikeouts in a single game when he struckout 21 Baltimore Orioles batters in a 16 inning game in 1962. Kerry Wood, Randy Johnson, and Roger Clemens (twice) hold the MLB record for most strikeouts in a 9 inning game with 20. == ==
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In MLB through games played on September 28, 2010 the most strikeouts in a game for Ichiro is 3 which he has done 11 times.
Bob Gibson holds the World Series record for most strikeouts by a pitcher in a World Series (35 in 1968) and most strikeouts by a pitcher in a single game (17 in Game 1 of the 1968 WS). He is tied for most games won by a pitcher in a World Series (3 in 1967).
bob gibsom
Randy Johnson - 19