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Aspirin is absorbed from the stomach but most of it is absorbed from small intestines because of poor dissolution of acidic drug in stomach acid, high dissolution in intestinal contents, large surface area on intestines and good blood flow in intestines

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Is aspirin absorbed in the stomach or intestines?

Aspirin is absorbed both in the stomach and the small intestine , for the former the cause lies beyond the fact that the gastric PH (1.5-2.5) is lower than the pka of aspirin (3.5) such that the ionization of aspirin is so much limited and the unionized and subsequently the lipophilicity of aspirin increases so that it's easily absorbed into the gastric mucosal cells. for the latter , aspirin absorption is due to the large absorptive surface area of the small intestine despite the fact that the intestinal PH is higher than the pka of aspirin , but still the surface area help absorption of the unionized fraction of aspirin.


Where in the digesitve system is absorption?

alcohol and aspirin are absorbed in the stomach, everything else is absorbed in the small intestine and excess water and vitamins k and b are absorbed in the large intestine.


Does aspirin dessolve?

yes. your stomach acids will dissolve the pill, and then the chemicals that make up the aspirin will be absorbed and stop the pain


Does aspirin dissolve in the stomach or small intestine?

Yes I am. After taking any medication for three to four days I develop cold and flu like symtoms. I now have an entry in my profile at the pharmacy to only dispense uncoated medication. They do and always have it available so others must have similar difficulties.


What substances are acitively absorbed in the stomach?

Aspirin and alcohol are two substances that are actively absorbed in the stomach.


What substances are actively absorb by the stomach?

Aspirin and alcohol are two substances that are actively absorbed in the stomach.


What are the only two substances that are absorbed across the stomach's mucosal epithelium?

Alcohol and aspirin are the only two substances that can be absorbed directly across the stomach's mucosal epithelium without needing to enter the bloodstream through the small intestine. This is because these substances are lipid-soluble and can pass through the cell membranes of the stomach lining.


Why patient with achlorhydria can dissolve aspirin rapidly?

Patients with achlorhydria have low or absent stomach acid, which is needed to break down aspirin for absorption. Without stomach acid, aspirin can dissolve quickly in the stomach and be absorbed more rapidly into the bloodstream, potentially leading to increased systemic effects and side effects.


Can the formula of aspirin be changed to produce less irritation to stomach?

Aspirin is "acetylsalicylic acid". Changing the chemical, changes the action. What is commonly done, is to coat the aspirin with a compound that does not let the aspirin dissolve in the stomach. This is called an "enteric coating". This helps a lot with stomach upset from taking regular aspirin.


Why would doctors recommend buffeting aspirin especially for those with a sensitive stomach?

The term is BUFFERED aspirin. Aspirin is an acid, and can cause stomach upset. Adding another substance to aspirin (a buffering material) can help counter the acid of the aspirin- and no tricky tummy.


What is the purpose of combining maalox with aspirin?

Maalox buffers the acidic effects on the stomach of the aspirin.


What is the difference between aspirin to buffered aspirin?

Buffered aspirin contains an additional ingredient, usually calcium carbonate or magnesium oxide, that helps to neutralize stomach acid and reduce irritation to the stomach lining. This makes buffered aspirin less likely to cause gastrointestinal side effects such as irritation, ulcers, or bleeding compared to regular aspirin.