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A glioblastoma (GBM) tumor itself can not cause constipation, unless the tumor location is affecting bowel movement or colon muscle coordination. Commonly, however, constipation in GBM patients is caused by chemotherapy drugs. It's important to stay on top of constipation issues for any cancer patient taking drugs, since a "small" issue like this can easily become a trip to the hospital emergency room for an enema. Even if patients have never suffered from constipation prior to cancer, they should consider taking prophylactic stool softeners while taking drugs which can cause constipation. Of course, many chemo drugs can also cause diarrhea. Some drugs, like the temozolomide (Temodar or Temodal) used in standard treatment of GBMs can cause constipation OR diarrhea; every patient reacts differently to drugs.

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Q: Can constipation be an effect of Glioblastoma?
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