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5HTP raises the neurotransmitter serotonin levels in the brain. Diazepam makes the neurotransmitter GABA more available in the brain. These two medications do not interact because they work on different neurotransmitters. They can be taken together.

Be carefull mixing 5HTP with other drugs which work on serotonin like: SSRI's like Prozac and other antidepressants, tricyclic antidepressants, tramadol, St John s Worth, XTC, etc. This will raise serotonin levels too high and can be dangerous.

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14y ago
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12y ago

I have been wondering the same thing. I have been taking a low dosage of Diazepam for a while now, but my low grade depression will not go away, so I've decided to throw a little 5-HTP in the mix, since SAM-E and St. Johns Wort didn't do anything. I will keep you updated on how it goes. Shouldn't be a problem though since they both work on different chemicals in the brain ie: 5-HTP increase seratonin, Diazepam works on GABA levels. Good luck

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Q: Can you take 5 htp with 5mg of diazepam safely together?
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