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first of all, I'm not in any medical profession, so this my personal experience. I've been on paroxetine (paxil) for 20 years now for a panic-disorder as they call it here.

Due to a slipped disk in my back I was on Oxycodone (Oxynorm, not the slow release

Oxycontin) for the last two months. After I took it I suspected some sort of interaction

between the two drugs. I once had 10 mg morfine after an operation 3 years ago, so I thougt I knew what to expect. My dose Paxil is 30 mg daily, Oxynorm 4 to 5 times a day 5 mg. I noticed shocks in my body and I became very exited and restless and the

pain was still there. After I reduced the Paxil to 22,5 mg a day, the Oxynorm works much better and 3 pills a day is enough to even walk the dog again! So what is going in your brain when you mix those drugs? I think the go for the same receptors in your brain and when its gets a bit crowded up there you experience

some sort of serotonine-overdose and that can lead to a dangerous medical

situation. So please ask your GP or chemist, all the best from Holland, Rick

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13y ago

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