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It is generally advised to consult with a healthcare professional before combining medications like Unisom PM, which contains diphenhydramine, with venlafaxine. Both substances can cause sedation and increase the risk of side effects such as dizziness or drowsiness. Your healthcare provider can give you personalized advice based on your medical history and current medications. Always prioritize safety and professional guidance when it comes to medication interactions.

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3mo ago

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