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The answer is: maybe, be cautious and get expert advice. I think the best rundown is found at this site: http://www.medscape.com/viewarticle/583836_11. Some relevant, pardon if I may quote:

Although the extent of allergic cross-reactivity between penicillin and cephalosporins is unknown and appears to be low, about 4% of patients with a proven penicillin allergy (by skin testing) also react to cephalosporins. Patients with a history of penicillin allergy who have negative penicillin skin test responses might safely receive cephalosporins. The AAAAI recommends that patients with a positive penicillin skin test (1) receive a non-beta-lactam antibiotic, (2) receive a cephalosporin through graded challenge, or (3) undergo rapid desensitization before receiving a cephalosporin. The clinical availability of skin test reagents would provide considerable assistance in evaluating patients with a history suggesting an IgE-type adverse drug response.

When current clinical data are combined with structural activity relationship side-chain analysis, it appears that, for select cephalosporins without side-chain similarities, the relative risk of prescribing these antibiotics in a non-IgE-mediated penicillin-allergic patient is no greater than the low inherent allergic risk of the products themselves.

Please note "cipro" is not a cephalosporin. It is a quinolone. The above appears to confuse the two.

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13y ago

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