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Yes you can, both are narcotic so you want to be careful of how much you put into your system. The most danger, other than overdose of the narcotic is, you really need to monitor the amount of aceteminophen (Tylenol) you injest. You will notice that a pill, such as percocete often has 5 mg of narcotic and 500 mgs of aceteminophen. Of course that amount varries from pill to pill (brand to brand), or (script to script). Just be careful Tylenol can pickle your liver....Esp if you drink alcohol

However, there is NO advantage of mixing 2 narcotic drugs. You should take only one and take higher dose if you want a better pain control (this adjustment must be done with your doctor).

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10y ago

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