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While you are able to take hydrocodone and Zoloft at the same time, it is highly recommended that you do not do so unless advised by a medical professional. The combination of the active sertraline in Zoloft and the hydrocodone can increase the risk of seratonin syndrome.

Whenever wondering about the side effects or dangers of prescription drugs, always consult a medical professional for the best advice.

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Kevin Stringer

Lvl 13
5y ago

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