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You can but only in low doses, as they both effect serotonin. I wouldn't take more than 50mg Elavil and 50mg 5 HTP daily. Exceeding this could cause a rare bu serious condition(serotonin syndrome).

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Phyllis Larkin

Lvl 10
2y ago
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12y ago

I just took the effexor and I took a 100mg 5 HTP like 15 minutes before. After about 30 more minutes I was uncontrolably throwing up and I had diarea. I had to poop like 3 times and was sick to my stomach for about 1-2 hours (its hard to concentrate on the time when your throwing up). I would also like to add that i am a casual smoker and had smoked pot about 1 our into the throwing up in between one of the stomach aches that were sooo increadibly painfully bad i was throwing up constantly...anyway, i did smoke a bowl in between and my stomachaches and the throwing up instantly went away. I would like to say this is 6 hours in and whenever my stomach startes to hurt again i am going to "roast" another doobie. I did however get on the internet and look up the side effects of effexor. Nausia was listed but i didnt think it would be that bad. SO, i am going to take the effexor alone tomorrow wothout the 5 HTP and see if I get sick to my stomach again. You sould see the comment bellow for my diagnosis to find out weather or not it was a side effect of the effexor (this is the first time I have taken it) or if it was a combined mixture of the Effexor and 5 HTP.

ok, it is the next day and I have edited this answer to include that I have sucessfully taken the Effexor following directions eating before I take it without the 5 HTP. I would also like to add that I took a multi-B vitamin supliment the day i took both the 5 HTP and Effexor. The B6 vitamin is supposed to help the 5 HTP create seritonin in your body.

My Conclusion. Dont take 5 HTP and Effexor together. I have been fine taking just the 5 HTP with multi B vitamin. I have taken the effexor by itself. but together I was very sick.

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15y ago

Yes, you can. 5-HTP converts to Seratonin in the brain. Some Seratonin converts to Melatonin. So, by taking Melatonin directly you are decreasing the amount of Seratonin that will be converted and therefore increasing the amount of Seratonin in the brain. So, both 5-HTP and Melatonin perform the same function of increasing seratonin levels. I use Melatonin (3mg) to help me sleep, and 5-HTP (50mg) to help with irritability during the day.

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13y ago

You can but only in low doses, as they both effect serotonin. I wouldn't take more than 50mg Elavil and 50mg 5 HTP daily. Exceeding this could cause a rare bu serious condition(serotonin syndrome).

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13y ago

yes my Dr perscribes both to me

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Q: Can you take melatonin and 5-HTP together?
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