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Laboratory Testing

Decreased serum albumin levels are seen in what condition?


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October 25, 2010 1:04PM

Cirrhosis of the Liver, and various liver diseases

Cirrhosis of the Liver, and various liver diseases

Albumin levels may be decreased in:

  • Dehydration
  • Hypothyroidism
  • Chronic debilitating diseases (ex: RA)
  • Malnutrition - Protein deficiency
  • Dilution by excess H2O (drinking too much water, which is termed "polydipsia," or excess administration of IV fluids)
  • Kidney losses (Nephrotic Syndrome)
  • Protein losing-enteropathy (protein is lost from the gastrointestinal tract during diarrhea)
  • Skin losses (burns, exfoliative dermatitis)
  • Liver dysfunction (the body is not synthesizing enough albumin and indicates very poor liver function)
  • Insufficient anabolic hormones such as Growth Hormone, DHEA, testosterone, etc

Correction: Albumin levels are actually increased during cases of dehydration; it is a relative increase because the there is a reduced volume of serum