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Analytical centrifugation is concerned mainly with the study of purified macromolecules(molar mass, shape etc) or isolated supra-molecular assemblies. This also allows to monitor the sample being spun through an optical detection system using ultraviolet light absorption and/or interference optical refractive index sensitive system.

While preparative centrifugation methodology is devoted to the actual methodology of separation of cells, sub-cellular structures, membrane vesicles and other particles of biochemical interest

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Q: Distinction between analytical centrifugation and preparative centrifugation?
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