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Just today I did an experiment for my chemistry class testing the rates at which Advil tablets, caplets, gel caplets, and Liquid-gels dissolve in simulated stomach acid. I used diluted Hydrochloric acid to simulate the stomach acid. I assume in water each will take longer to dissolve, but they will still dissolve in the same order.
In the acid, Caplets and Tablets both opened completely and were a fine powder on the bottom of the container after 10 minutes.
After 30 minutes, the Liquid-gel had gotten soft and the contents leaked out from two spots. It took over an hour and a half for all of the contents to leave the gel coating.
The Gel Caplets I really recommend taking only if the three above are not available. After and hour and a half, the coating became soft but was not open anywhere. When I finally removed it from the acid, the coating tore and inside was the ibuprofin powder, completely dry and shaped just like the original pill.
So quickest to slowest dissolving rate:
Caplets/Tablets, Liquid-Gels, Gel Caplets

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14y ago
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16y ago

Yes, the liquid gel caps are made to dissolve quickly so the liquid inside can hit you faster thus releiving pain faster.

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Q: Do Advil pm liquid gel caps work faster than Advil tablets?
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