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Some water molecules form a hydration shell around hydrophilic solute molecules through adhesion. These are referred to as bound water molecules, and are unable to diffuse freely across the plasma membrane. A dilute solution is a solution that contains more solvent than solute. In dilute biological fluids, the difference in the proportion of unbound water molecules causes osmosis, rather than the difference in water concentration.

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Q: Explain how bound water affects the osmotic behavior of dilute biological fluids?
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