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To encounter Brian Meech in GTA IV for the third, and last time, you have to wait one game-time week after the first meeting.

Niko can then meet him on the corner of Montauk Avenue, close to the gun shop in Broker. He will ask Niko to take him to see some drug dealers in order to pay what he owes them, as he has mended his ways after going into rehab. Unfortunately the two dealers will attack Brian, so Niko has to go and rescue him. Once this has been achieved and Niko takes Brian back home, there will be a $500 reward.

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Q: Grand Theft Auto 4 when do you do Brian's 3rd mission?
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