Yes, they made their debut at SkyDome in 1995, and played a majority of their games their or some at Maple Leaf Gardens when SkyDome was unavailable. They played at SkyDome until 1999 when the Air Canada Centre opened.
Brian Bowles debuted on June 27, 2001, playing for the Toronto Blue Jays at Skydome; he played his final game on September 8, 2003, playing for the Toronto Blue Jays at Skydome.
Rob Butler debuted on June 12, 1993, playing for the Toronto Blue Jays at Skydome; he played his final game on July 10, 1999, playing for the Toronto Blue Jays at Skydome.
Pasqual Coco debuted on July 17, 2000, playing for the Toronto Blue Jays at Skydome; he played his final game on April 14, 2002, playing for the Toronto Blue Jays at Skydome.
Ken Robinson debuted on July 20, 1995, playing for the Toronto Blue Jays at Skydome; he played his final game on September 24, 1997, playing for the Toronto Blue Jays at Skydome.
Jimmy Rogers debuted on July 30, 1995, playing for the Toronto Blue Jays at Skydome; he played his final game on September 27, 1995, playing for the Toronto Blue Jays at Skydome.
Mike Romano debuted on September 5, 1999, playing for the Toronto Blue Jays at Skydome; he played his final game on September 24, 1999, playing for the Toronto Blue Jays at Skydome.
Andy Thompson debuted on May 2, 2000, playing for the Toronto Blue Jays at Skydome; he played his final game on May 4, 2000, playing for the Toronto Blue Jays at Skydome.
Jeff Ware debuted on September 2, 1995, playing for the Toronto Blue Jays at Skydome; he played his final game on July 7, 1996, playing for the Toronto Blue Jays at Skydome.
Scott Wiggins debuted on September 11, 2002, playing for the Toronto Blue Jays at Skydome; he played his final game on September 20, 2002, playing for the Toronto Blue Jays at Skydome.
Shannon Withem debuted on September 18, 1998, playing for the Toronto Blue Jays at Skydome; he played his final game on September 18, 1998, playing for the Toronto Blue Jays at Skydome.
Joe Lawrence debuted on April 8, 2002, playing for the Toronto Blue Jays at Skydome; he played his final game on July 22, 2002, playing for the Toronto Blue Jays at Skydome.
Doug Linton debuted on August 3, 1992, playing for the Toronto Blue Jays at Skydome; he played his final game on April 18, 2003, playing for the Toronto Blue Jays at Skydome.