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How are belladonna alkaloids used as a medication?

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βˆ™ 2007-06-21 16:05:52

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The mostly widely used alkaloid from Atropa belladonnaplants is atropine, which is a tropane alkaloid.

Some of its uses include:

  • Antidote to the toxic effects of cholinesterase inhibitors since it is a known anticholinergic, and therefore, prevents the toxic effects that can result due to accumulation of acetylcholine in the neuromuscular junctions and the parasympathetic nervous system.
  • Sometimes used by optometrists and opthalmologists as a cycloplegic, which paralyzes the accommodation reflex and thus induces mydriasis (pupil dilation) during eye examination.
Several belladonna alkaloids as well are used in combination with phenobarbital to relieve cramping pains, in cases such as irritable bowel syndrome
2007-06-21 16:05:52
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