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Since the area surrounding Autoimmune diseases are so uncertain and not very well understood, it is hard to say for certain what triggers autoimmune diseases as a whole or even seperately. There have been some theories that the Epstein-Barr virus (mononucleosis) play a role in setting it off but there are also other theories ranging from job related repeated vibrations setting off Scleroderma to the coxsackie virus being a risk factor for having Type 1 Diabetes (insulin dependent). Though there are many theories, they are still under consideration and being tested.

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