Nerve agents inhibit the transfer of messages between the brain or spinal cord, and the recipient muscle/organ/etc. In effect, they disable the body's ability to pass messages and information through the peripheral nervous system. Without this communication, the various bodily functions quickly cease to work properly - breathing can stop, the heart can beat improperly (or not at all), muscles refuse to move various body parts (or move them incorrectly).
Think of the body as having an old-style telephone system in it, with the brain and spinal cord as the Central Office where the operator sits. Normally, messages pass through the telephone lines, to the Central Office, where the Operator decides where to patch the call to, in order to reach the correct destination. Nerve agents cut the wires from the houses to the Central Office, making it impossible to talk to either the Operator or any other house.
they inhibit the enzyme Acetylcholinesterase (AChE) allowing Acetylcholine (ACh) to accumulate.
they inhibit the enzyme Acetylcholinesterase (AChE) allowing Acetylcholine (ACh) to accumulate.
nerve agents
Neurotransmission
Nerve agents effect the junctions between nerve cells. Nerve agents prevent signals crossing the nerve junctions so all communication between nerve cells stops and no signals can get through from the brain.
Nerve agents typically affect the acetylcholine system by irreversibly binding to the enzyme, acetylcholinesterase. This prevents the body from catabolizing acetylcholine, resulting in an accumulation of the neurotransmitter in the synapse and neuromuscular junction.
Nerve agents typically send signals to your brain to make your body contract. This specific nerve agent is especially deadly due to its ability to kill so easily. A fatal dose on the skin is only 10mg, and can easily kill you within hours (even minutes). These nerve agents kill you by asphyxia.
Nerve agents are class of phosphorus containing organic chemicals that disrupt the mechanism by which nerves transfer messages to organs. The disruption is caused by blocking acetyl-interscholastic, an enzyme that normally destroys tetracycline, a neurotransmitter.
Nerve Agents are also known as nerve gases. They disrupt the mechanism by which nerves transfer messages to the organs. ---- More specifically, nerve agents interfere with the transmission of messages along nerves, interfering with the chemical interactions that pass a message from one end of a nerve cell to the next nerve cell. They disrupt the electro-chemical processes at the synapses (junctions between nerve cells) by blocking acetylcholinesterase, a key enzyme. By inhibiting nerve message passing, they prevent key messages from being sent to various critical body functions. As such, they cause involuntary muscle spasms in increasing intensity, and eventually lead to fatal asphyxia as the loss of respiratory control progresses.
Chemical agents may be classified persistent, nonpersistent and dusty. Threat forces classify chemicalagents according to their effect on the body. They identify six major types--nerve, blood, blister,choking, psychochemical, and irritants.Persistent chemical agents are used to produce casualties (immediate or delayed). Immediate casualties occur when a person inhales the vapor. Delayed casualtiesoccur and is absorbed through the skin demonstrating the need for protective equipment.
Nerve Agents are also known as nerve gases. They disrupt the mechanism by which nerves transfer messages to the organs. ---- More specifically, nerve agents interfere with the transmission of messages along nerves, interfering with the chemical interactions that pass a message from one end of a nerve cell to the next nerve cell. They disrupt the electro-chemical processes at the synapses (junctions between nerve cells) by blocking acetylcholinesterase, a key enzyme. By inhibiting nerve message passing, they prevent key messages from being sent to various critical body functions. As such, they cause involuntary muscle spasms in increasing intensity, and eventually lead to fatal asphyxia as the loss of respiratory control progresses.
Nerve agents work by blocking a hormone called cholinesterase. A nerve is basically a pipe. When your body wants to send information down a nerve, it puts a little bit of the hormone acetylcholine into it. When it wants to stop sending, it shoots some cholinesterase down the pipe, and the cholinesterase "turns off" the acetylcholine. (There's more to it than that, but you get the idea.) By stopping cholinesterase from working, your whole body just goes into convulsions and, eventually, you just seize up. Very nasty way to die.
Chemical agents may be classified persistent, nonpersistent and dusty. Threat forces classify chemicalagents according to their effect on the body. They identify six major types--nerve, blood, blister,choking, psychochemical, and irritants.Persistent chemical agents are used to produce casualties (immediate or delayed). Immediate casualties occur when a person inhales the vapor. Delayed casualtiesoccur and is absorbed through the skin demonstrating the need for protective equipment.