Oncogene - journal - was created in 1987.
A proto-oncogene is normally converted to an oncogene by mutation of the gene that encodes the proto-oncogene. Often, this leads to de-regulation of the proto-oncogenes activity and typically abarrent signal transduction in the cell, which may lead to cellular transformation.
An oncogene is a gene, when mutated or expressed at high levels it helps turn a normal cell into a tumor cell.
Oncogene.
Compare with a virus: dormant to active, potential to kinetic, potent(ial) to actual. The proto-oncogene may become a cancer-causing oncogene only under very specific conditions and may, under other conditions, just as well lay dormant.
oncogene
any gene that is a causative factor in the initiation of cancerous growth
oncogene
oncogene
you will have to be more specific There is a point mutation in the k-ras oncogene, and about 60% have a mutation in the p53 so you can develop cancer in the colon by many polyps.
to a gene
tumor suppresser gene that could turn into an oncogene