How does the endoplasmic reticulum make proteins?

Answer 1

Ones proteins are synthesized into the rough ER they undergo some modifications (folding, glycosylation) and then the mature, correctly folded proteins are passed to the Golgi apparatus via transport vesicles. Save

Answer 2

Firstly, ribosomes are a Protein Manufacture construct; they are not made for transport, with the following exception;

secondly, there are two types of ribosomal, newly synthesized proteins: one - those that, when after ribosomal construction is completed, are 'directedly' released 'toward their target-areas' into the cytoplasm; and those that are released into the intra-Smooth-Endoplasmic-Reticulum cavity, for direct distribution to various addressed destinations towards the Cell's extremities.

Answer 3

It doesn't. Some polypeptides are threaded right into the lumen of the ER from the ribosomes, but ribosomes " make " proteins by threading the mRNA through them while tRNA is bringing individual amino acids to the ribosome. The ER does modify proteins, generally with carbohydrates, while the proteins are in the ER.

Answer 4

The protein contains a molecular zip code that allows the protein to be shipped to the correct cellular compartment.