An enzyme is shaped so that a specific substrate can attatch to it. A lock and a key function in a similar way. Each lock is shaped so that only a certain key can open it.
The lock and key model means that the substrate must perfectly fit the enzyme, and the enzyme does not change. The induced fit model is different as when the substrate fits together with the enzyme, the enzyme itself will change to either join substrates together or break a substrate down.
The lock is the equivalent to that of an enzyme while the key is portrayed as the substrate. Like an enzyme, the lock can be reused many times as it remains chemically unchanged at the end of the reaction. Also, the fact that reactions occur only at the active site, or binding site, is showed as the key only being able to open the lock only at the keyhole, not anywhere else. The hypothesis also shows the fact that enzymes can only catalyse a specific substrate, showed as the lock, only being able to open with a specific key. Firstly,the substrate will enter the active side of the enzyme.then,the enzyme will change it shape slightly as the substrate binds.During this time,the substrate will be broken down.After that,the product will leave the active sides of the enzyme.
In biology the lock and key method states that an enzyme and it's substrate are complementary and only the correct substrate can bind with the enzyme, this is due to the folding in the protein structure. However this theory is outdated and the inducted fit method is a much better representation.
Induced fit: is a more recent theory which suggests that the substrate attaches to the enzyme in a relatively accurate fit, then the enzyme moulds around it, then continues the chemically complex reaction. Lock and Key Mechanism: As obvious as the name states, the lock and key model is simply the substrate fitting acutely into the enzyme with no adjustments required to the enzyme. K.G. ;)
It means that an enzyme will only work on one specific substrate at a time, because no meaningful biochemical activity can occur without their absolute specificity.We are talking about 30,000 bio-enzymatically controlled Biochemical reactions.In the Chem Lab a product yield of 60 percent is a huge achievement.In the Body anything less than a 100 percent yieldwould swiftly result in the Cell being overwhelmed by the useless by-products of these 30,000 biochemical Reactions.
It is when the enzyme (lock) fits exactly into the substrate (key) forming an enzyme substrate complex. It refers to enzymes and their substrates. The enzyme has an active site (lock) where the substrate that is complemetary fits in (key). Only substrates that fit perfectly into the enzymes active site will active the particular reaction, just like only 1 specific key will open a door.
The Key is the substrate while the key is the enzyme. Just finished learning this :)
lock-and-key model
matching of enzyme with the substrate
lock and key theory
There is an enzyme explanation whose specificity states that an enzyme and its substrate possess specific complementary geometric shapes that fit exactly into one another. This is the lock and key explanation.Ê
The lock and key model means that the substrate must perfectly fit the enzyme, and the enzyme does not change. The induced fit model is different as when the substrate fits together with the enzyme, the enzyme itself will change to either join substrates together or break a substrate down.
Enzymes have an active site that is specific for a substrate - therefore enzymes only work when the right substrate is present. The surfaces of the enzyme and the substrate fit together - like a lock and key - allowing the enzyme to fulfil its function. The theory of "induced fit" is more widely accepted - it is similar, but the enzyme shape changes to accommodate the substrate.
The substrate fits inside the active site of the enzyme. when it fits perfectly its called " lock and key"
The lock is the equivalent to that of an enzyme while the key is portrayed as the substrate. Like an enzyme, the lock can be reused many times as it remains chemically unchanged at the end of the reaction. Also, the fact that reactions occur only at the active site, or binding site, is showed as the key only being able to open the lock only at the keyhole, not anywhere else. The hypothesis also shows the fact that enzymes can only catalyse a specific substrate, showed as the lock, only being able to open with a specific key. Firstly,the substrate will enter the active side of the enzyme.then,the enzyme will change it shape slightly as the substrate binds.During this time,the substrate will be broken down.After that,the product will leave the active sides of the enzyme.
The substrate fits into the enzyme, much the way a key fits in a lock. Sometimes there are other "modulators" that also fit in the enzyme.
Lock and key is an analogy of enzyme catalysis in a cellular reaction. The lock and key are compared directly to the substrate and enzyme, because of the high specificity of their physical shape. Enzymes participate in the reaction they catalyze. The reactant molecule (substrate) binds to the enzyme molecule at a particular location called the active site. (this is compared to the lock with keyhole) The highly specific nature of an enzyme is due to very precisely defined arrangement of atoms in the active site(again, this is the lock in the analogy). The substrate molecule must have a matching shape (here is the key) that will fit into the active site. The bond breaking and bond forming processes that transform the substrate into products occur while the substrate is bound to the active site of enzyme. In other words its something like a jigsaw puzzle where the substrate fits into the enzyme. The reaction occurs and the substrate then leaves the enzyme as products. ( Not my work. Found it on Yahoo Answers.....Do not give me credit...Thought I should do this to help people out =] ) Edited answer for readability and clarity - thanks!