Depending if usen once or for years it can be 3 days if sometimes user it can be 7plus if ur a long time user..
About 3-4 hours depending you are really in pain or not or if you took them to just take them. About 3-4 hours depending you are really in pain or not or if you took them to just take them.
I am sorry but we can't answer because we don't know what "it" is. You need to give the name of what you want the answer to.
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