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Claritin is an antihistamine that take a bit longer to build up in your system as opposed to the older antihistamines like Benadryl. The plus side is there is minimal drowsiness. For a drug to reach 90% of it's steady state levels after constant usage, it takes about 3.3 half lives, so it takes about a day for Claritin (8hr half life) to get to it's maximal effectiveness. It doesn't cause drowsiness because it doesn't cross the blood-brain barrier like earlier antihistamines, such as Benadryl.

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12y ago
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12y ago

About an hour or two, depending on how full your stomach is.

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10y ago

According to Health Tap's website it takes approximately one to three hours for Claritin D to begin working. This medication is considered "fast acting".

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