Mapquest lists the distance between Minneapolis, MN and Des Moines, IA as 243.59 miles and a driving time of 3 hours 45 minutes.
24 hours
It is a 12 hour drive.
25 hours
About 4 hrs.
About 14 hours.
9 hours
Just about two hours.
28 hours
10 hours
It will take you about 20 hours to drive the 1198 miles between the two locations.
six hours
4-6 hours