The driving distance between Buffalo, NY and Louisville, KY is approximately 535 miles. The driving time would be approximately 8 hours 30 minutes if you were to travel non-stop in good driving conditions. (The driving time does not take into consideration conditions which may extend trip time such as weather, road work, border crossings and rush hour traffic in urban areas.)
It depends on where you are going in Louisville. From Frankfort to the east side of Louisville the drive is 35-40 minutes.
Almost 14 hours.
5 hours
According to MapQuest and depending on where you start out in Louisville and go to in Birmingham, it will take at least 5 hours and 35 minutes to drive.
Check Mapquest.com
According to mapquest.com, it will take approx. 16 1/2 hours to drive the 1083.76 miles from Miami Florida to Louisville Kentucky.
34 hours
Three days
Buffalo to Cleveland is three hours
Chigago IL to Louisville, KY, USA 297 mi - about 4 hours 47 mins
It is 106.67 miles according to MapQuest.
three and a half hours