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from I-485 @ Johnston Road to Bethune, SC is one hour and ten minutes. Take hwy 521 south to Lancaster.Then exit on hwy 9/521 to the exit of hwy 903 east. When hwy 346 sign appears at Mount Pisgah Baptist Church, turn right on hwy 346. Follow 346 to Bethune (about 12 miles).

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15y ago
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Q: How long does it take to drive from charlotte nc to bethune sc?
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